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Cell Signaling Technology Inc phosphorylated p38mapk

Effects of dietary vitamin D 3 supplementation on jejunal phosphorylation levels of PKA, PKC, PI3K, <t>p38MAPK,</t> and ERK in broiler chickens (19 d) (Experiment 1). The control and vitamin D 3 diets contained 0 and 1000 IU/kg vitamin D 3 , respectively. (a) p-PKA/t-PKA; (b) p-PKC/t-PKC; (c) p-PI3K/t-PI3K; (d) <t>p-p38MAPK/t-p38MAPK;</t> (e) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Phosphorylated P38mapk, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1900 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+p38mapk/Phospho-p38+MAPK+(Thr180%2FTyr182)+Mouse+mAb/pmc13011214-154-29-39
Average 96 stars, based on 1900 article reviews

phosphorylated p38mapk - by Bioz Stars, 2026-10

96/100 stars

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1) Product Images from "PKA and PKC signaling pathways mediate vitamin D₃-regulated intestinal phosphorus absorption in broiler chickens"

Article Title: PKA and PKC signaling pathways mediate vitamin D₃-regulated intestinal phosphorus absorption in broiler chickens

Journal: Poultry Science

doi: 10.1016/j.psj.2026.106762

Effects of dietary vitamin D 3 supplementation on jejunal phosphorylation levels of PKA, PKC, PI3K, p38MAPK, and ERK in broiler chickens (19 d) (Experiment 1). The control and vitamin D 3 diets contained 0 and 1000 IU/kg vitamin D 3 , respectively. (a) p-PKA/t-PKA; (b) p-PKC/t-PKC; (c) p-PI3K/t-PI3K; (d) p-p38MAPK/t-p38MAPK; (e) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Figure Legend Snippet: Effects of dietary vitamin D 3 supplementation on jejunal phosphorylation levels of PKA, PKC, PI3K, p38MAPK, and ERK in broiler chickens (19 d) (Experiment 1). The control and vitamin D 3 diets contained 0 and 1000 IU/kg vitamin D 3 , respectively. (a) p-PKA/t-PKA; (b) p-PKC/t-PKC; (c) p-PI3K/t-PI3K; (d) p-p38MAPK/t-p38MAPK; (e) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Techniques Used: Phospho-proteomics, Control, Quantitative Proteomics

Effects of the PKA inhibitor H-89 on jejunal phosphorylation levels of PKC, PI3K, p38MAPK, and ERK in broiler chickens (10–15 d) (Experiment 2). (a) p-PKC/t-PKC; (b) p-PI3K/t-PI3K; (c) p-p38MAPK/t-p38MAPK; (d) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Figure Legend Snippet: Effects of the PKA inhibitor H-89 on jejunal phosphorylation levels of PKC, PI3K, p38MAPK, and ERK in broiler chickens (10–15 d) (Experiment 2). (a) p-PKC/t-PKC; (b) p-PI3K/t-PI3K; (c) p-p38MAPK/t-p38MAPK; (d) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Techniques Used: Phospho-proteomics, Quantitative Proteomics

Effects of the PKC inhibitor staurosporine on duodenal phosphorylation levels of PKA, PI3K, p38MAPK, and ERK in broiler chickens (13 d) (Experiment 3). (a) p-PKA/t-PKA; (b) p-PI3K/t-PI3K; (c) p-p38MAPK/t-p38MAPK; (d) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Figure Legend Snippet: Effects of the PKC inhibitor staurosporine on duodenal phosphorylation levels of PKA, PI3K, p38MAPK, and ERK in broiler chickens (13 d) (Experiment 3). (a) p-PKA/t-PKA; (b) p-PI3K/t-PI3K; (c) p-p38MAPK/t-p38MAPK; (d) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Techniques Used: Phospho-proteomics, Quantitative Proteomics

other:

Article Title: ALKBH5 exacerbates early cardiac damage after radiotherapy for breast cancer via m6A demethylation of TLR4
Article Snippet: Primary antibodies included: anti-METTL3 (ab195352), anti-METTL14 (ab309096), anti-WTAP, (ab195380), anti-ALKBH5 (ab195377), anti-FTO (ab126605), anti-TLR4 (sc-293072; Santa Cruz, Dallas, TX, USA), anti-p-P38MAPK (4511; Cell Signaling Technology, Danvers, MA, USA), anti-p-ERK1/2 (4370; CST), anti-p-JNK (4668; CST), anti-p-NF-κB (3033; CST), anti-P38MAPK (8690; CST), anti-ERK1/2 (4695; CST), anti-JNK (9252; CST), anti-NF-κB (8242; CST), and anti-β-actin (ab8227).

Article Title: Inhibitory effects of high extracellular l -glutamate concentrations on skeletal myogenesis
Article Snippet: Anti-pp38MAPK (T180/Y182) (1:500, Cat# 9216S), anti-p38MAPK (1:500, Cat# 8690S), anti-pCREB (S133) (1:500, Cat# 9198S), anti-CREB (1:500, Cat# 9104S), anti-β-tubulin (1:500, Cat# 2128S), anti-N-cadherin (1:500, Cat# 14215S) and anti-p53 (1:500, Cat# 2524S) were from Cell signaling technology (Beverly, MA, USA).

Article Title: Salidroside Selectively Binds to SEC23A and Ameliorates Psychological Stress-Induced Hyperpigmentation.
Article Snippet: Primary antibodies were anti-Actin (Abcam, ab7817, Cambridge, UK); anti-MITF-M (Abcam, ab20663); anti-TYR (Abcam, ab180753); anti-glyceraldehyde 3-phosphate dehydrogenase (GAPDH; Abcam, ab8245); anti-p-CREB (Cell Signaling Technology, 9198); anti-CREB (Cell Signaling Technology, 9197, Massachusetts, MA, USA); anti-β-catenin (Cell Signaling Technology, 9567); anti-GSK (Cell Signaling Technology, 9562); anti-p-GSK (Cell Signaling Technology, 79774); anti-AKT (Cell Signaling Technology, 9272); anti-p-AKT (Cell Signaling Technology, 4060), anti-p-p38 (Cell Signaling Technology, 9211); anti-p38MAPK (Cell Signaling Technology, 9212); anti-p-ERK (Cell Signaling Technology, 9101); anti-ERK (Cell Signaling Technology, 9102); anti-p-JNK (Cell Signaling Technology, 9251); anti-JNK (Cell Signaling Technology, 9252); anti-MC1R (Cell Signaling Technology, 9595); anti-PKA (Abcam, ab32514); anti-NK1R (Abcam, ab75516); anti-tyrosinase (TYR)-related protein-1 (TRP-1; Abcam, ab235447); and anti-dopachrome tautomerase (DCT; Abcam, ab221144); anti-SEC23A (abclonal, A8613, Wuhan, Hubei, China).

Article Title: Inhibitory effects of high extracellular L-glutamate concentrations on skeletal myogenesis.
Article Snippet: Antipp38MAPK (T180/Y182) (1:500, Cat# 9216S), anti-p38MAPK (1:500, Cat# 8690S), anti-pCREB (S133) (1:500, Cat# 9198S), anti-CREB (1:500, Cat# 9104S), anti-β-tubulin (1:500, Cat# 2128S), anti-N-cadherin (1:500, Cat# 14215S) and anti-p53 (1:500, Cat# 2524S) were from Cell signaling technology (Beverly, MA, USA).

Article Title: Salidroside Selectively Binds to SEC23A and Ameliorates Psychological Stress-Induced Hyperpigmentation
Article Snippet: Primary antibodies were anti-Actin (Abcam, ab7817, Cambridge, UK); anti-MITF-M (Abcam, ab20663); anti-TYR (Abcam, ab180753); anti-glyceraldehyde 3-phosphate dehydrogenase (GAPDH; Abcam, ab8245); anti-p-CREB (Cell Signaling Technology, 9198); anti-CREB (Cell Signaling Technology, 9197, Massachusetts, MA, USA); anti-β-catenin (Cell Signaling Technology, 9567); anti-GSK (Cell Signaling Technology, 9562); anti-p-GSK (Cell Signaling Technology, 79774); anti-AKT (Cell Signaling Technology, 9272); anti-p-AKT (Cell Signaling Technology, 4060), anti-p-p38 (Cell Signaling Technology, 9211); anti-p38MAPK (Cell Signaling Technology, 9212); anti-p-ERK (Cell Signaling Technology, 9101); anti-ERK (Cell Signaling Technology, 9102); anti-p-JNK (Cell Signaling Technology, 9251); anti-JNK (Cell Signaling Technology, 9252); anti-MC1R (Cell Signaling Technology, 9595); anti-PKA (Abcam, ab32514); anti-NK1R (Abcam, ab75516); anti-tyrosinase (TYR)-related protein-1 (TRP-1; Abcam, ab235447); and anti-dopachrome tautomerase (DCT; Abcam, ab221144); anti-SEC23A (abclonal, A8613, Wuhan, Hubei, China).

Article Title: Hydrogen sulfide donor GYY4137 attenuates RANKL-induced osteoclast differentiation and multi-nucleation.
Article Snippet: Anti-JNK1/2, anti-phospho-JNK1/2, anti-ERK1/2, anti- phospho-ERK1/2, anti-p38MAPK, anti-phospho-p38MAPK, and antibodies were purchased from Cell Signaling Technology, Inc. (Beverly, MA, USA).

Article Title: ( +)-Catechin Alleviates CCI-Induced Neuropathic Pain by Modulating Microglia M1 and M2 Polarization via the TLR4/MyD88/NF-κB Signaling Pathway.
Article Snippet: The aim of this research endeavor was to explore the therapeutic potential of ( +)-catechin in mitigating neuropathic pain.. A total of thirty-two Sprague‒Dawley rats were randomly allocated into four groups: the sham group, the chronic constriction injury (CCI) group, the CCI + ibuprofen group, and the CCI + ( +)-catechin group.. The results of the in vivo experiment show that ( +)-catechin has the potential to improve mechanical hyperalgesia induced by CCI and reduce the infiltration of inflammatory cells in the injured sciatic nerve.

Western Blot:

Article Title: Structure-activity relationships reveal a 4-(2-pyridyl)chalcone as a potent cell death inducer.
Article Snippet: .. The primary antibodies used for immunoblots were obtained from the following companies (all at 1:1000 dilution): anticaspase-3 (#ADI-AAP-113) was from Enzo (Ann Arbor, MI, USA); anticaspase-9 (#9502), anti-caspase-8 (#9746), anti-Bcl-2 (#4223), antiBax (#2772), anti-phospho-JNK/SAPK (phosphor T183 + Y185) (#9251), anti-JNK/SAPK (#9252), anti-phospho-p44/42 MAPK (Erk1/ 2) (Thr202/Tyr204) (#9101), anti-p44/42 MAP Kinase (ERK1/2) (#9102), anti-phospho-p38MAPK (T180/Y182) (#9211), anti-p38MAPK (#9212), and anti-α-tubulin (#2125) antibodies from Cell Signaling Technology (Beverly, MA, USA). .. Anti-PARP [poly(ADP-ribose) polymerase] (#551024) and anti-cytochrome c (#556433) were from BD Pharmingen (San Diego, CA, USA); anti-DR4 (ab8414) was from Abcam (Cambridge, UK).

Image Search Results

Effects of OST on cardiac autophagy and the p38MAPK/mTOR signaling pathway in TRZ-treated mice. (A–B) Representative images of transmission electron microscopy images, yellow arrow, mitochondria; red arrow, autophagosome. (C) Representative western blotting bands for LC3I, LC3II, Beclin-1, p62. (D–F) Quantitative analysis of LC3II/I, Beclin-1, p62 (normalized to GAPDH). (G) Representative western blotting bands for p-p38MAPK, p38MAPK, p-mTOR and mTOR. (H) Quantitative analysis of p-p38MAPK/p38MAPK and p-mTOR/mTOR. Data are expressed as means ± SEM ( n = 3). ## P < 0.01 vs the CON group; ∗ P < 0.05, ∗∗ P < 0.01 vs the TRZ group.

Journal: Journal of Traditional and Complementary Medicine

Article Title: Osthole attenuates trastuzumab-induced cardiotoxicity in mice by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway

doi: 10.1016/j.jtcme.2025.06.001

Figure Lengend Snippet: Effects of OST on cardiac autophagy and the p38MAPK/mTOR signaling pathway in TRZ-treated mice. (A–B) Representative images of transmission electron microscopy images, yellow arrow, mitochondria; red arrow, autophagosome. (C) Representative western blotting bands for LC3I, LC3II, Beclin-1, p62. (D–F) Quantitative analysis of LC3II/I, Beclin-1, p62 (normalized to GAPDH). (G) Representative western blotting bands for p-p38MAPK, p38MAPK, p-mTOR and mTOR. (H) Quantitative analysis of p-p38MAPK/p38MAPK and p-mTOR/mTOR. Data are expressed as means ± SEM ( n = 3). ## P < 0.01 vs the CON group; ∗ P < 0.05, ∗∗ P < 0.01 vs the TRZ group.

Article Snippet: The first antibodies to Bax (1:1000 dilution, A0207), Bcl-2 (1:800 dilution, A0208), Caspase-3 (1:800 dilution, A2156), LC3 (1:500 dilution, A19665), Beclin-1 (1:1000 dilution, A7353), p62 (1:1000 dilution, A19700) and GAPDH (1:800 dilution, A19056) were purchased from ABclonal Company (Wuhan, China), p38MAPK (1:1000 dilution, bs-0637R) and p-p38MAPK (1:1000 dilution, bs-0636R) were purchased from Bioss Company (Beijing, China), mTOR (1:1000 dilution, #2983) and p-mTOR (1:1000 dilution, #2971) were purchased from CST Company (Danvers, MA, USA).

Techniques: Transmission Assay, Electron Microscopy, Western Blot

Effects of OST on autophagy and the p38MAPK/mTOR signaling pathway in TRZ-treated mice after SB203580 administration. (A–B) Representative images of transmission electron microscopy images, yellow arrow, mitochondria; red arrow, autophagosome. (C) Representative western blotting bands for LC3I, LC3II, Beclin-1, p62. (D–F) Quantitative analysis of LC3II/I, Beclin-1, p62 (normalized to GAPDH). (G) Representative western blotting bands for p-mTOR and mTOR. (H) Quantitative analysis of p-mTOR/mTOR. Data are expressed as means ± SEM ( n = 3). # P < 0.05, ## P < 0.01 vs the CON group; ∗ P < 0.05, ∗∗ P < 0.01 vs the TRZ group; ▲ P < 0.05, ▲▲ P < 0.01 vs the TRZ + OST H group.

Journal: Journal of Traditional and Complementary Medicine

Article Title: Osthole attenuates trastuzumab-induced cardiotoxicity in mice by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway

doi: 10.1016/j.jtcme.2025.06.001

Figure Lengend Snippet: Effects of OST on autophagy and the p38MAPK/mTOR signaling pathway in TRZ-treated mice after SB203580 administration. (A–B) Representative images of transmission electron microscopy images, yellow arrow, mitochondria; red arrow, autophagosome. (C) Representative western blotting bands for LC3I, LC3II, Beclin-1, p62. (D–F) Quantitative analysis of LC3II/I, Beclin-1, p62 (normalized to GAPDH). (G) Representative western blotting bands for p-mTOR and mTOR. (H) Quantitative analysis of p-mTOR/mTOR. Data are expressed as means ± SEM ( n = 3). # P < 0.05, ## P < 0.01 vs the CON group; ∗ P < 0.05, ∗∗ P < 0.01 vs the TRZ group; ▲ P < 0.05, ▲▲ P < 0.01 vs the TRZ + OST H group.

Techniques: Transmission Assay, Electron Microscopy, Western Blot

Schematic illustration summarizing the protective effects of OST against TRZ-induced cardiotoxicity by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway.

Journal: Journal of Traditional and Complementary Medicine

Article Title: Osthole attenuates trastuzumab-induced cardiotoxicity in mice by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway

doi: 10.1016/j.jtcme.2025.06.001

Figure Lengend Snippet: Schematic illustration summarizing the protective effects of OST against TRZ-induced cardiotoxicity by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway.

Techniques:

Journal: Poultry Science

Article Title: PKA and PKC signaling pathways mediate vitamin D₃-regulated intestinal phosphorus absorption in broiler chickens

doi: 10.1016/j.psj.2026.106762

Figure Lengend Snippet: Effects of dietary vitamin D 3 supplementation on jejunal phosphorylation levels of PKA, PKC, PI3K, p38MAPK, and ERK in broiler chickens (19 d) (Experiment 1). The control and vitamin D 3 diets contained 0 and 1000 IU/kg vitamin D 3 , respectively. (a) p-PKA/t-PKA; (b) p-PKC/t-PKC; (c) p-PI3K/t-PI3K; (d) p-p38MAPK/t-p38MAPK; (e) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Article Snippet: PVDF membranes were incubated with primary antibodies against NaPi-IIb (1:1000, A9460; ABclonal, Wuhan, China), phosphorylated PKA (p-PKA; 1:1000, 5661S), phosphorylated PI3K (p-PI3K; 1:1000, 4228), phosphorylated ERK (p-ERK; 1:1000, 9101S), phosphorylated p38MAPK (p-p38MAPK; 1:1000, 9216S), total PKA (t-PKA; 1:1000, 5842S) (Cell Signaling Technology, Boston, USA), total PI3K (t-PI3K; 1:10000, 60225-1-Ig), total ERK (t-ERK; 1:8000, 11257-1-AP-50), total p38MAPK(t-p38MAPK; 1:1000, 14064-1-AP), total PKC (t-PKC; 1:1000, 21991-1-AP), phosphorylated PKC (p-PKC; 1:5000, 29123-1-AP), and GAPDH (1:10000, 60004-1-Ig) (Proteintech, Wuhan, China).

Techniques: Phospho-proteomics, Control, Quantitative Proteomics

Journal: Poultry Science

Article Title: PKA and PKC signaling pathways mediate vitamin D₃-regulated intestinal phosphorus absorption in broiler chickens

doi: 10.1016/j.psj.2026.106762

Figure Lengend Snippet: Effects of the PKA inhibitor H-89 on jejunal phosphorylation levels of PKC, PI3K, p38MAPK, and ERK in broiler chickens (10–15 d) (Experiment 2). (a) p-PKC/t-PKC; (b) p-PI3K/t-PI3K; (c) p-p38MAPK/t-p38MAPK; (d) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Techniques: Phospho-proteomics, Quantitative Proteomics

Journal: Poultry Science

Article Title: PKA and PKC signaling pathways mediate vitamin D₃-regulated intestinal phosphorus absorption in broiler chickens

doi: 10.1016/j.psj.2026.106762

Figure Lengend Snippet: Effects of the PKC inhibitor staurosporine on duodenal phosphorylation levels of PKA, PI3K, p38MAPK, and ERK in broiler chickens (13 d) (Experiment 3). (a) p-PKA/t-PKA; (b) p-PI3K/t-PI3K; (c) p-p38MAPK/t-p38MAPK; (d) p-ERK/t-ERK. Protein abundance values are means ± SD of four replicates per treatment (1 broiler per replicate) (n = 4). Values with different letters differ between treatments ( P < 0.05).

Techniques: Phospho-proteomics, Quantitative Proteomics

Journal: Poultry Science

Article Title: PKA and PKC signaling pathways mediate vitamin D₃-regulated intestinal phosphorus absorption in broiler chickens

doi: 10.1016/j.psj.2026.106762

Techniques: Phospho-proteomics, Control, Quantitative Proteomics

Journal: Poultry Science

Article Title: PKA and PKC signaling pathways mediate vitamin D₃-regulated intestinal phosphorus absorption in broiler chickens

doi: 10.1016/j.psj.2026.106762

Techniques: Phospho-proteomics, Quantitative Proteomics

Journal: Poultry Science

Article Title: PKA and PKC signaling pathways mediate vitamin D₃-regulated intestinal phosphorus absorption in broiler chickens

doi: 10.1016/j.psj.2026.106762

Techniques: Phospho-proteomics, Quantitative Proteomics

Journal: Journal of Traditional and Complementary Medicine

Article Title: Osthole attenuates trastuzumab-induced cardiotoxicity in mice by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway

doi: 10.1016/j.jtcme.2025.06.001

Techniques: Transmission Assay, Electron Microscopy, Western Blot

Journal: Journal of Traditional and Complementary Medicine

Article Title: Osthole attenuates trastuzumab-induced cardiotoxicity in mice by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway

doi: 10.1016/j.jtcme.2025.06.001

Techniques: Transmission Assay, Electron Microscopy, Western Blot

Journal: Journal of Traditional and Complementary Medicine

Article Title: Osthole attenuates trastuzumab-induced cardiotoxicity in mice by enhancing autophagy via regulating the p38MAPK/mTOR signaling pathway

doi: 10.1016/j.jtcme.2025.06.001

Techniques:

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phosphorylated p38mapk (Cell Signaling Technology Inc)

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